Analysis of Postoperative Ocular Surface Changes and Intervention Effect After PPV in MGD Dry Eye Patients
Summary
AIM: To observe ocular surface changes after phacovitrectomy in patients with mild to moderate meibomian gland dysfunction (MGD)-type dry eye and track clinical treatment response using a Keratograph 5M and a LipiView interferometer. METHODS: Forty cases were randomized into control group A and treatment group B; the latter received meibomian gland treatment 3 days before phacovitrectomy and sodium hyaluronate before and after surgery. The average non-invasive tear film break-up time (NITBUTav), first non-invasive tear film break-up time (NITBUTf), non-invasive measured tear meniscus height (NTMH), meibomian gland loss (MGL), lipid layer thickness (LLT) and partial blink rate (PBR) were measured preoperatively and 1 week, 1 month and 3 months postoperatively.
Timeline
- Start
- 2021-02-01
- Primary completion
- 2022-03-20
- Completion
- 2022-07-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Sodium Hyaluronate | Other / unclassified | 0.1 % | Topical |
| Background | Fluorometholone | Other / unclassified | 0.1 % | — |
| Background | Gatifloxacin | Small molecule | — | Topical |
| Background | Pranoprofen | Small molecule | — | — |
| Background | tropicamide | Small molecule | — | — |