The Effect of Aprepitant Reducing Postoperative Nausea and Vomiting

Summary

The purpose of this study is to assess the efficacy of Aprepitant + standard antiemetic regimen in reducing postoperative nausea and vomiting after laparoscopic gastric sleeve versus placebo + standard antiemetic regimen

Timeline

Start

2022-12-01

Primary completion

2023-01-01

Completion

2023-04-01

Publications

• Ortiz E, Gonzalez AI, Jaime V, Guzman JA, Esparza I, Orozco JO, Guerrero MA, Ramos A, Zerrweck C. The impact of Aprepitant on Nausea and Vomiting following Laparoscopic Sleeve Gastrectomy: A Blinded Randomized Controlled Trial. Obes Surg. 2024 Apr;34(4):1316-1323. doi: 10.1007/s11695-024-07129-0. Epub 2024 Mar 2.

Drugs

Indications