drugset / Trial / NCT05790707
EfFect of Ablation of Persistent AtriaL Fibrillation on COgNitive Function in Individuals With Mild Cognitive Impairment
RandomizedParallel-groupSingle-blindTreatment
Summary
The goal of this clinical trial is to evaluate the effect of catheter ablation of persistent atrial fibrillation on cognitive function in patients with mild cognitive impairment. Participants will be randomized into antiarrhythmic drugs alone or atrial fibrillation ablation + antiarrhythmic drugs.
Timeline
- Start
- 2023-04-21
- Primary completion
- 2027-01
- Completion
- 2027-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amiodarone | Small molecule | — | — |
| Comparator | flecainide | Small molecule | — | — |
| Comparator | propafenone | Unknown | — | — |
| Comparator | sotalol | Small molecule | — | — |