drugset / Trial / NCT05791136

Immunotherapy After Radiotherapy in Elderly ESCC

NCT05791136 ↗

Phase 2 Unknown 30 enrolled The Central Hospital of Lishui City
NaSingle-groupOpen-labelTreatment

Summary

The incidence and mortality of esophageal squamous cell carcinoma are at the forefront in China.Most part of patients are elderly. Concurrent chemoradiotherapy is the standard treatment for unresectable locally advanced esophageal squamous cell carcinoma. Most elderly patients cannot tolerate concurrent chemotherapy because of complications and other reasons. Immunotherapy has definite efficacy and low toxicity in advanced esophageal squamous cell carcinoma, and the results combined with radiotherapy have also been preliminarily reported. Therefore, it is necessary to further explore the efficacy and safety of radiotherapy combined with immunotherapy in elderly patients with esophageal squamous cell carcinoma.

Timeline

Start
2023-04
Primary completion
2024-04-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Toripalimab Monoclonal antibody 200 mg Intravenous