drugset / Trial / NCT05791669
Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride Solution
RandomizedParallel-groupDouble-blindTreatment
Summary
This study was conducted to assess the efficacy of 38% Silver Diamine fluoride and compare it with 5% sodium fluoride varnish in arresting interproximal caries in primary molars at 12 months follow-up. Bitewing radiographs were taken to diagnose as well as to assess caries depth at follow up visits. Each bitewing was scored based on ICCMS radiographic criteria and was compared (follow-ups to baseline)to check for caries arrest. Interproximal caries included in this study, according to ICCMS criteria, were at stages- RA - caries limited to outer half of enamel RA2 - caries limited to the inner half of enamel RA3 - caries limited to outer third of dentine RA4 - caries limited to middle third of dentine
Timeline
- Start
- 2021-08-01
- Primary completion
- 2022-08-02
- Completion
- 2022-11-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Duraphat | Unknown | 5 % | Topical |
| Subject | silver diammine fluoride | Small molecule | 38 % | Topical |