drugset / Trial / NCT05791669

Arrest of Interproximal Caries Lesion With 38% Silver Diamine Fluoride Solution

NCT05791669

Phase 3 Completed 45 enrolled Postgraduate Institute of Dental Sciences Rohtak
RandomizedParallel-groupDouble-blindTreatment

Summary

This study was conducted to assess the efficacy of 38% Silver Diamine fluoride and compare it with 5% sodium fluoride varnish in arresting interproximal caries in primary molars at 12 months follow-up. Bitewing radiographs were taken to diagnose as well as to assess caries depth at follow up visits. Each bitewing was scored based on ICCMS radiographic criteria and was compared (follow-ups to baseline)to check for caries arrest. Interproximal caries included in this study, according to ICCMS criteria, were at stages- RA - caries limited to outer half of enamel RA2 - caries limited to the inner half of enamel RA3 - caries limited to outer third of dentine RA4 - caries limited to middle third of dentine

Timeline

Start
2021-08-01
Primary completion
2022-08-02
Completion
2022-11-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Duraphat Unknown 5 % Topical
Subject silver diammine fluoride Small molecule 38 % Topical

Indications