drugset / Trial / NCT05807347

Venetoclax Combined With Azacitidine and CAG in Refractory/Relapse Acute Myeloid Leukemia

NCT05807347

Phase 2 Unknown 42 enrolled Hematology department of the 920th hospital
NaSingle-groupOpen-labelTreatment

Summary

This study aims to assess the therapeutic efficacy and safety of venetoclax in combination with azacitidine and CAG as induction regimen in Patients with Refreactory/Relapse Acute Myeloid Leukemia.

Timeline

Start
2023-02-01
Primary completion
2024-02-01
Completion
2026-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Venetoclax Small molecule 400 mg Oral
Background Aclacinomycin Unknown 12 mg/m2
Background Aclacinomycin Unknown 14 mg/m2
Background Azacitidine Other / unclassified 75 mg/m2 Subcutaneous
Background Cytarabine Small molecule 10 mg/m2 Subcutaneous