drugset / Trial / NCT05813535

8.4% Sodium Bicarbonate Locks in Intestinal Failure

NCT05813535

Phase 2 Completed 6 enrolled Riad Rahhal
NaSingle-groupOpen-labelPrevention

Summary

We plan to include children with intestinal failure, a condition where the gut is not functioning properly, leading these children to need central venous catheters (line that goes through the skin into the blood stream) for nutritional support and hydration. Such patients have a very high risk for catheter infection. The study will include placing an agent (sodium bicarbonate) into the central catheter when the catheter is not in use. This is referred to as a lock. The lock would be used daily and removed when patients start their nutritional support and hydration through the catheter.

Timeline

Start
2022-12-01
Primary completion
2025-03-01
Completion
2025-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject sodium bicarbonate Diagnostic / imaging agent 8.4 % Other