drugset / Trial / NCT05818826

Early Versus Conventional Cessation of Hydrocortisone in Septic Shock

NCT05818826

Phase 2 Unknown 160 enrolled Mahidol University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Septic shock is one of the causes of death in ICU and hospital. Refractory shock is the problem which healthcare providers should recognize though it is difficult to handle with. The corticosteroid called hydrocortisone is one of the treatment in refractory septic shock which requires vasopressor to maintain blood pressure. In recovery phase of septic shock and weaning off vasopressor, there is no definite way to taper off hydrocortisone.

Timeline

Start
2023-07-05
Primary completion
2025-04
Completion
2025-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Hydrocortisone Other / unclassified 200 mg