drugset / Trial / NCT05829239

ADI-PEG20, Obesity and Prediabetes

NCT05829239

RandomizedParallel-groupDouble-blindTreatment

Summary

Th purpose of this study is to determine whether ADI-PEG20 (PEGylated arginine deiminase), an arginine catabolizing enzyme preparation, improves insulin sensitivity, mitochondrial respiration, and energy utilization in adolescents with prediabetes.

Timeline

Start
2024-04-01
Primary completion
2024-04-01
Completion
2024-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pegargiminase Protein / enzyme biologic 18 mg/m2 Intramuscular