drugset / Trial / NCT05834569

Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients

NCT05834569

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The primary aim of this interventional study is to investigate the impact of perioperative administration of Maxigesic (combination of acetaminophen and ibuprofen) on delirium after minimally invasive lung surgery in elderly patients. The Maxigesic group receives a total of 5 doses of Maxigesic (20mg/kg, maximum dose per serving: 1g) every 6 h from immediately after anesthesia induction. The control group receives the same volume of normal saline. Researchers compare the incidence and severity of postoperative delirium for 5 days after surgery.

Timeline

Start
2023-06-15
Primary completion
2025-01-23
Completion
2025-01-23

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule Intravenous
Subject Ibuprofen Small molecule Intravenous

Indications