drugset / Trial / NCT05834569
Impact of Maxigesic on Delirium After Minimally Invasive Lung Surgery in Elderly Patients
RandomizedParallel-groupQuadruple-blindPrevention
Summary
The primary aim of this interventional study is to investigate the impact of perioperative administration of Maxigesic (combination of acetaminophen and ibuprofen) on delirium after minimally invasive lung surgery in elderly patients. The Maxigesic group receives a total of 5 doses of Maxigesic (20mg/kg, maximum dose per serving: 1g) every 6 h from immediately after anesthesia induction. The control group receives the same volume of normal saline. Researchers compare the incidence and severity of postoperative delirium for 5 days after surgery.
Timeline
- Start
- 2023-06-15
- Primary completion
- 2025-01-23
- Completion
- 2025-01-23
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Acetaminophen | Small molecule | — | Intravenous |
| Subject | Ibuprofen | Small molecule | — | Intravenous |