drugset / Trial / NCT05845424

High-intensity Statin and Ezetimibe Therapy for Asymptomatic Patients With Positive Coronary Calcium

NCT05845424

Phase 4 Recruiting 6000 enrolled Samsung Medical Center
RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of this study is to compare safety and efficacy between the aggressive treatment with combination of high-intensity statin and ezetimibe and the current standard lipid lowering treatment in asymptomatic patients with presence of coronary calcification.

Timeline

Start
2023-07-03
Primary completion
2029-06-30
Completion
2030-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Ezetimibe Unknown 10 mg
Comparator Rosuvastatin Small molecule 5 mg
Comparator Rosuvastatin Small molecule 20 mg