drugset / Trial / NCT05854498

Liposomal Irinotecan With TAS102 and Bevacizumab for Patients With Metastatic Colorectal Cancer

NCT05854498

Phase 2 Recruiting 50 enrolled University of Wisconsin, Madison Ipsen · collab
NaSingle-groupOpen-labelTreatment

Summary

This study is being done to see if combining liposomal irinotecan with TAS102 and bevacizumab confers clinical benefit for patients with treatment refractory metastatic colorectal cancer.

Timeline

Start
2023-10-13
Primary completion
2028-07
Completion
2028-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody 5 mg/kg Intravenous
Subject Irinotecan Small molecule 50 mg/m2 Intravenous
Subject TAS-102 Small molecule 35 mg/m2 Oral

Indications