drugset / Trial / NCT05862337

Anlotinib Hydrochloride Capsules Combined With Penpulimab Injection for the Treatment of Hepatocellular Carcinoma at High Risk of Recurrence.

NCT05862337

Phase 3 Recruiting 480 enrolled Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary objective of this study was to evaluate the efficacy of anlotinib hydrochloride capsules combined with penpulimab injection (test group) versus placebo (control group) for adjuvant therapy after radical surgery or ablation in HCC patients with high risk of recurrence by assessing recurrence-free survival (RFS).

Timeline

Start
2023-05-10
Primary completion
2024-08
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Catequentinib Small molecule
Subject Penpulimab Monoclonal antibody