drugset / Trial / NCT05871541

A First-in-Human Study to Evaluate JCXH-105, an SrRNA-based Herpes Zoster Vaccine

NCT05871541

Phase 1 Completed 75 enrolled Immorna Biotherapeutics, Inc. ICON plc · collab
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of this clinical trial is to assess the safety and immunogenicity of a self-replicating (sr) RNA-based vaccine, JCXH-105, in the prevention of Shingles (Herpes Zoster) Participant will be randomized to receive either JCXH-105 or Shingrix.

Timeline

Start
2023-05-26
Primary completion
2024-03-25
Completion
2024-03-25

Drugs

EvaluationDrugModalityDoseRoute
Subject JCXH-105 Other / unclassified Intramuscular
Comparator VARICELLA ZOSTER VIRUS ENVELOPE GLYCOPROTEIN E Vaccine Intramuscular

Indications