drugset / Trial / NCT05874401

Trilaciclib vs Placebo in Patients With Extensive Stage Small Cell Lung Cancer (ES-SCLC) Receiving Topotecan

NCT05874401

Phase 4 Recruiting 302 enrolled Pharmacosmos A/S
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a multicenter, randomized, double-blind, placebo-controlled study to assess whether trilaciclib administered prior to topotecan is non-inferior to placebo administered prior to topotecan with regard to overall survival.

Timeline

Start
2023-10-18
Primary completion
2027-10-30
Completion
2027-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Trilaciclib Unknown 240 mg/m2 Intravenous
Background Topotecan Small molecule 1.5 mg/m2 Intravenous