drugset / Trial / NCT05885399

The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic Treatment

NCT05885399

Phase 2 Unknown 5 enrolled Peking Union Medical College Hospital
NaSingle-groupOpen-labelTreatment

Summary

Metastatic pheochromocytoma / paraganglioma (MPP) are rare while the prognosis was poor. Penpulimab is specifically an immune check-point inhibitor of PD1 and has been approved for the treatment of several malignancies.This phase II trial studies the efficacy and safety of penpulimab in the treatment of MPP patients who fail to other systemic therapy.

Timeline

Start
2023-04-01
Primary completion
2025-03-01
Completion
2025-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Penpulimab Monoclonal antibody 200 mg Intravenous