drugset / Trial / NCT05887804
Comparison of Keloid Volume and Symptoms Reduction Between Intralesional Umbilical-Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide Injection as Keloid Therapy: A Randomised Controlled Trial
Phase 4
Completed
24 enrolled
Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Indonesia University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This study is a double-blind randomized controlled trial (RCT) examining the effect of intralesional injection of umbilical cord-derived mesenchymal stem cells (UC-MSC), umbilical cord-derived conditioned medium (UC-CM), or triamcinolone acetonide (TA) on keloids carried out using CONSORT statement. Research is directed at studying keloid volume reduction and changes in POSAS score.
Timeline
- Start
- 2021-10-01
- Primary completion
- 2022-06-09
- Completion
- 2022-06-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Triamcinolone Acetonide | Other / unclassified | 40 mg/ml | Other |
| Subject | mesenchymal stem cells | Cell therapy | 2e+06 cells | Other |
| Subject | umbilical cord-derived mesenchymal stem cells conditioned medium | Unknown | 1 ml | Other |