drugset / Trial / NCT05895929
The Role of IL5 in Epithelial Cell Integrity
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The goal of this laboratory study is the examine the effect of mepolizumab drug on the health and function of the cells lining the human nasal airways in vitro cell culture derived from patients with chronic rhinosinusitis with nasal polyposis. The main questions the study aims to study are: 1. To see what mepolizumab does to suppress inflammation of the human cells. 2. To see what mepolizumab does to maintain barrier integrity of epithelial cells
Timeline
- Start
- 2023-09-05
- Primary completion
- 2025-12-31
- Completion
- 2026-02-27
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Mepolizumab | Monoclonal antibody | — | — |