drugset / Trial / NCT05901714
A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam
Non-randomizedSequentialOpen-labelTreatment
Summary
This study will consist of 2 parts. The study will evaluate whether administration of phenytoin impacts the single-dose drug levels of afimetoran and BMT-271199 (Part 1) and will evaluate whether multiple administrations of afimetoran impact the drug levels of midazolam and 1-hydroxymidazolam (Part 2).
Timeline
- Start
- 2023-06-14
- Primary completion
- 2024-04-11
- Completion
- 2024-04-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Afimetoran | Small molecule | — | — |
| Subject | Midazolam | Small molecule | — | — |
| Subject | Phenytoin | Unknown | — | — |
Indications
No indication recorded.