drugset / Trial / NCT05904808
The Heart Failure Diuresis Efficacy Comparison (DEA-HF) Study
RandomizedCrossoverOpen-labelTreatment
Summary
To investigate the effectiveness of three (3) IV diuretic regimens to increase natriuresis in volume-overloaded HF patients, allowing for better decongestion and potentially resulting in improved clinical and biochemical parameters outcome.
Timeline
- Start
- 2023-04-19
- Primary completion
- 2023-08-01
- Completion
- 2023-08-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetazolamide | Small molecule | 500 mg | Intravenous |
| Comparator | Metolazone | Small molecule | 5 mg | Oral |
| Comparator | Furosemide | Other / unclassified | 250 mg | Intravenous |