A Study to Compare the Effects of Improving the Carotid Artery Intima Media Thickness and Changing Lipid Levels by Cilostazol/Ginkgo Leaf Extract and Aspirin in Diabetic Peripheral Angiopathy.

Phase 4 Completed 105 enrolled SK Chemicals Co., Ltd.

RandomizedParallel-groupOpen-labelTreatment

Summary

This study is to compare and evaluate the effect of improving the carotid IMT and lipid level of the Cilostazol/Ginkgo leaf extract group with the aspirin administrated group in patients with diabetic peripheral angiopathy.

Timeline

Start: 2021-07-28
Primary completion: 2023-06-23
Completion: 2023-12-13

Publications

Hwang YC, Kim MK, Park JH, Yun HM, Kim SY, Lim S. Comparison of Efficacy and Safety of Cilostazol/Extract of Ginkgo biloba vs. Aspirin in Carotid Atherosclerosis in Patients with Diabetes Mellitus. Diabetes Metab J. 2026 Mar;50(2):357-367. doi: 10.4093/dmj.2025.0146. Epub 2025 Aug 13.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Aspirin	Small molecule	100 mg	Oral
Subject	Cilostazol	Small molecule	200 mg	Oral
Subject	Extract of Ginkgo Biloba	Unknown	160 mg	Oral

A Study to Compare the Effects of Improving the Carotid Artery Intima Media Thickness and Changing Lipid Levels by Cilostazol/Ginkgo Leaf Extract and Aspirin in Diabetic Peripheral Angiopathy.

Summary

Timeline

Publications

Drugs

Indications