drugset / Trial / NCT05909059
CAR T-cell Therapy in Patients With Renal Dysfunction
Phase 2
Recruiting
20 enrolled
Northside Hospital, Inc.
Blood and Marrow Transplant Group of Georgia · collab
Non-randomizedSingle-groupOpen-labelTreatment
Summary
This is a prospective, descriptive study designed to assess the feasibility of administering CAR T therapy among patients with moderate to severe renal impairment using dose adjusted lymphodepleting chemotherapy.
Timeline
- Start
- 2024-11-18
- Primary completion
- 2026-08-31
- Completion
- 2027-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | — | Intravenous |
| Subject | Fludarabine | Small molecule | — | Intravenous |