Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

Summary

This is a prospective, multicenter, non-randomized, open label light dose escalation phase I trial to evaluate the safety and preliminary efficacy of Padeliporfin vascular targeted photodynamic therapy (VTP) applied via endovascular fiber placement within a dilatation catheter, through the target artery(superior mesenteric artery (SMA), celiac artery (CA) or common hepatic artery (CHA)). The investigators will evaluate safety and preliminary efficacy of Padeliporfin VTP administered endovascularly using light dose escalation.

Timeline

Start

2024-05-15

Primary completion

2026-05-30

Completion

2026-10-30

Drugs

Indications