drugset / Trial / NCT05922345

Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy.

NCT05922345

RandomizedParallel-groupQuadruple-blindTreatment

Summary

To investigate the efficacy of AL2846 capsules in combination with TQB2450 injection or Docetaxel injection in patients with advanced NSCLC who have previously failed immune checkpoint inhibitors (anti-PD-1 monoclonal antibody, anti-PD-L1 monoclonal antibody), regardless of new anti-tumor treatment and early termination of treatment.

Timeline

Start
2023-06-08
Primary completion
2025-08
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Subject AL2846 Small molecule
Subject Benmelstobart Monoclonal antibody
Comparator Docetaxel Small molecule