drugset / Trial / NCT05922345
Evaluation of the Efficacy and Safety of AL2846 Capsule Combined With TQB2450 Injection Compared to Docetaxel Injection in Advanced Non-small Cell Lung Cancer Patients Who Have Failed With Immunotherapy.
RandomizedParallel-groupQuadruple-blindTreatment
Summary
To investigate the efficacy of AL2846 capsules in combination with TQB2450 injection or Docetaxel injection in patients with advanced NSCLC who have previously failed immune checkpoint inhibitors (anti-PD-1 monoclonal antibody, anti-PD-L1 monoclonal antibody), regardless of new anti-tumor treatment and early termination of treatment.
Timeline
- Start
- 2023-06-08
- Primary completion
- 2025-08
- Completion
- 2025-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AL2846 | Small molecule | — | — |
| Subject | Benmelstobart | Monoclonal antibody | — | — |
| Comparator | Docetaxel | Small molecule | — | — |