drugset / Trial / NCT05927259

The Role of N-acetylcysteine as a Novel Adjuvant Treatment in Acute Organophosphorus Pesticide Poisoning

NCT05927259

Phase 0 Completed 40 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelTreatment

Summary

All patients admitted in the ICU of the PCC-ASUH due to acute poisoning by acute organophosphorus poisoning will be included in the study. The diagnosis of intoxication will be based on history of acute exposure , clinical examination and laboratory investigations. Patients will be randomly allocated into 2 equal groups. Group 1 -. Patients who will receive (conventional treatment of acute organophosphorus poisoning plus NAC) and Group 2 - Patients who will receive conventional treatment only

Timeline

Start
2022-01-01
Primary completion
2023-05-01
Completion
2023-06-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator N-acetylcysteine Small molecule 70 mg/kg Intravenous