drugset / Trial / NCT05933642
Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The goal of this RCT is to compare the effectiveness of aminophylline and furosemide combination vs furosemide alone in producing effective diuresis in critically ill adults in ICU. ICU patients with the need of improved diuresis will be recruited and given either infusion of aminophylline and furosemide combination or furosemide alone, and their hourly urine output will be monitored to compare their effectiveness.
Timeline
- Start
- 2023-07-02
- Primary completion
- 2023-12-31
- Completion
- 2023-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aminophylline | Small molecule | 150 mg | Intravenous |
| Comparator | Furosemide | Other / unclassified | 120 mg | Intravenous |