drugset / Trial / NCT05933642

Diuretic Efficacy of Aminophylline and Furosemide Combination vs Furosemide Alone in Critically Ill Adults

NCT05933642

Phase 2/3 Unknown 132 enrolled University of Malaya
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of this RCT is to compare the effectiveness of aminophylline and furosemide combination vs furosemide alone in producing effective diuresis in critically ill adults in ICU. ICU patients with the need of improved diuresis will be recruited and given either infusion of aminophylline and furosemide combination or furosemide alone, and their hourly urine output will be monitored to compare their effectiveness.

Timeline

Start
2023-07-02
Primary completion
2023-12-31
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Aminophylline Small molecule 150 mg Intravenous
Comparator Furosemide Other / unclassified 120 mg Intravenous

Indications