drugset / Trial / NCT05939817
The Effect of Intralesian Injection of Umbilical Cord Mesenchymal Stem Cells, Its Conditioned Medium, and Triamcinolone Acetonide on Type 1:3 Collagen Ratio and Interleukin-10 Levels in Keloid: A Randomised Controlled Trial
Phase 4
Completed
24 enrolled
Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Indonesia University · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The objective of this study is to observe the potency of umbilical cord-derived mesenchymal stem cells (UC-MSC) and umbilical cord-derived conditioned medium (UC-CM), or triamcinolone acetonide (TA) in keloid therapy, measured by the decrease in the type 1:3 collagen ratio and the increase of IL-10 levels carried out using CONSORT statement.
Timeline
- Start
- 2021-10-01
- Primary completion
- 2022-06-09
- Completion
- 2022-06-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Triamcinolone Acetonide | Other / unclassified | 40 mg | Other |
| Subject | mesenchymal stem cells | Cell therapy | 2e+06 cells | Other |
| Subject | umbilical cord-derived mesenchymal stem cells conditioned medium | Unknown | 1 ml | Other |