drugset / Trial / NCT05942378

A Study of HRXG-K-1939 and Adebrelimab in Patients With Advanced Solid Tumors

NCT05942378

Phase 1 Unknown 30 enrolled Fudan University
NaSequentialOpen-labelTreatment

Summary

This is a Phase 1, open-label study evaluating the efficacy and safety of HRXG-K-1939 in combination with Adebrelimab (anti-programmed death-ligand 1 \[anti-PD-L1\] antibody) in patients with advanced solid tumors. HRXG-K-1939 will be administered to patients in a dose escalation regimen to determine a recommended dose for expansion.

Timeline

Start
2023-07-01
Primary completion
2025-09-01
Completion
2025-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject HRXG-K-1939 Messenger RNA (mRNA)
Background Adebrelimab Monoclonal antibody

Indications