Drugs / Adebrelimab
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Adebrelimab

also known as SHR-1316 · ADE · Adebrelimab Injection · Ariel

Monoclonal antibody targets CD274 via inhibition

Developed for
small cell lung carcinoma · non-small cell lung carcinoma · esophageal squamous cell carcinoma · hepatocellular carcinoma · cancer · breast cancer · biliary tract cancer · malignant pancreatic neoplasm
+48 more · colorectal cancer · intrahepatic cholangiocarcinoma · gastric cancer · gastroesophageal junction adenocarcinoma · hormone receptor-positive breast cancer · triple-negative breast carcinoma · esophageal cancer · gastric adenocarcinoma · head and neck squamous cell carcinoma · neoplasm · gastroesophageal adenocarcinoma · cervical cancer · cholangiocarcinoma · female breast carcinoma · nasopharyngeal carcinoma · biliary tract neoplasm · carcinoma · gastroesophageal cancer · Her2-receptor negative breast cancer · metastatic malignant neoplasm in the brain · oral cavity squamous cell carcinoma · rectal cancer · urinary bladder carcinoma · urothelial carcinoma · breast carcinoma · castration-resistant prostate carcinoma · digestive system carcinoma · esophageal small cell neuroendocrine carcinoma · gastric neoplasm · hypopharynx cancer · Langerhans cell histiocytosis · liver cancer · lung disorder · mature T-cell and NK-cell non-Hodgkin lymphoma · metastatic malignant neoplasm · metastatic prostate carcinoma · neoplastic disease or syndrome · neuroendocrine carcinoma · neuroendocrine neoplasm · osteosarcoma · ovarian cancer · pancreatic adenocarcinoma · pancreatic ductal adenocarcinoma · peripheral T-cell lymphoma, not otherwise specified · rectal carcinoma · rectum adenocarcinoma · thyroid cancer · urinary bladder cancer
Investigated by
Suzhou Suncadia Biopharmaceuticals Co., Ltd. · Jiangsu HengRui Medicine Co., Ltd. · Fudan University · Sun Yat-sen University · Tianjin Medical University Cancer Institute and Hospital · Shanghai Hengrui Pharmaceutical Co., Ltd.
+124 more · Jiangsu Hengrui Pharmaceutical Co., Ltd. · Peking University Cancer Hospital & Institute · Cancer Institute and Hospital, Chinese Academy of Medical Sciences · Harbin Medical University · Shanghai Shengdi Pharmaceutical Co., Ltd · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Fujian Cancer Hospital · Tang-Du Hospital · The First Affiliated Hospital with Nanjing Medical University · Shanghai Zhongshan Hospital · The First Affiliated Hospital of Xiamen University · West China Hospital · Hansoh BioMedical R&D Company · Henan Cancer Hospital · Nanfang Hospital, Southern Medical University · Tongji Hospital · Zhejiang Cancer Hospital · Atridia Pty Ltd. · First Affiliated Hospital of Fujian Medical University · First Hospital of China Medical University · Fujian Medical University Union Hospital · Hebei Medical University Fourth Hospital · Jiangsu Hansoh Pharmaceutical Co., Ltd. · Jinling Hospital, China · Liaoning Cancer Hospital & Institute · Nanjing Tianyinshan Hospital · Ningbo Medical Center Lihuili Hospital · Peking Union Medical College Hospital · Ruijin Hospital · Shandong Suncadia Medicine Co., Ltd. · Shanghai Chest Hospital · Shanghai Pulmonary Hospital, Shanghai, China · Shanghai Regenelead Therapies Co., Ltd. · Shengjing Hospital · The First Affiliated Hospital of Zhengzhou University · Union Hospital, Tongji Medical College, Huazhong University of Science and Technology · Zhangzhou Municipal Hospital · Affiliated Hospital of Guangdong Medical University · Affiliated Hospital of Nantong University · Air Force Military Medical University, China · Anhui Provincial Hospital · Baohui Han · Beijing 302 Hospital · Beijing Chest Hospital · Beijing Chest Hospital, Capital Medical University · Beijing Friendship Hospital · Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center · Cancer Hospital of Guangxi Medical University · Changhai Hospital · Chen Chunyan · China Medical University, China · Chinese PLA General Hospital · Chongqing University Cancer Hospital · Feng Tian · First Affiliated Hospital Xi'an Jiaotong University · Fujian Provincial Hospital · Gansu Provincial Cancer Hospital · Guangdong Provincial People's Hospital · Henan Provincial People's Hospital · Hospital of Stomatology, Wuhan University · Huazhong University of Science and Technology · HuiKai Li · Hunan Provincial Cancer Hospital · Jiang Long · Jiangmen Central Hospital · Jiangsu Cancer Institute & Hospital · Jilin Provincial Cancer Hospital · Jilin Provincial Tumor Hospital · Jin Xu · Jin Ying · Jinming Yu · Jinshazhou Hospital of Guangzhou University of Chinese Medicine · Jun Jia · Lei ZHAO · all 130 on the full record

Trials 255 · started per year

today
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20182019202020212022202320242025202620272028
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 03 trials
Phase 0 NCT06735508 Jan 2025 → Dec 2026 expected non-small cell lung carcinoma Guangdong Provincial People's Hospital Not yet recruiting No outcome recorded
Phase 0 NCT06156267 Jan 2024 → Apr 2026 overdue pancreatic adenocarcinoma Fudan University Not yet recruiting No outcome recorded
Phase 0 NCT06685653 ? → Nov 2026 expected non-small cell lung carcinoma Nanjing Tianyinshan Hospital Not yet recruiting No outcome recorded
Phase 118 trials
Phase 1 NCT07063407 Jul 2025 → Apr 2026 overdue small cell lung carcinoma Shanghai Hansoh Biomedical Co., Ltd Not yet recruiting No outcome recorded
Phase 1 NCT07009457 Jun 2025 → Sep 2027 expected small cell lung carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Active not recruiting No outcome recorded
Phase 1 NCT06963502 May 2025 → Dec 2028 expected colorectal cancer, non-small cell lung carcinoma Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06902792 Feb → Aug 2025 overdue Langerhans cell histiocytosis Second Affiliated Hospital of Wenzhou Medical University Enrolling by invitation No outcome recorded
Phase 1 NCT06699576 Dec 2024 → Dec 2026 expected osteosarcoma, soft tissue sarcoma Hansoh BioMedical R&D Company Not yet recruiting No outcome recorded
Phase 1 NCT06594874 Oct 2024 → Oct 2026 expected non-small cell lung carcinoma Jiangsu Hansoh Pharmaceutical Co., Ltd. Not yet recruiting No outcome recorded
Phase 1 NCT06332170 Apr 2024 → May 2026 overdue neoplastic disease or syndrome Hansoh BioMedical R&D Company Recruiting No outcome recorded
Phase 1 NCT06336707 Apr 2024 → Apr 2026 overdue cancer Hansoh BioMedical R&D Company Recruiting No outcome recorded
Phase 1 NCT06225921 Dec 2023 → Jan 2025 esophageal squamous cell carcinoma West China Hospital Unknown No outcome recorded
Phase 1 NCT06181032 Dec 2023 → Feb 2029 expected biliary tract cancer First Affiliated Hospital of Fujian Medical University Recruiting No outcome recorded
Phase 1/228 trials
Phase 1/2 NCT07615283 May 2026 → May 2030 expected mature T-cell and NK-cell non-Hodgkin lymphoma, peripheral T-cell lymphoma, not otherwise specified Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 1/2 NCT07595172 Apr 2026 → Aug 2028 expected pancreatic ductal adenocarcinoma West China Hospital Recruiting No outcome recorded
Phase 1/2 NCT07392541 Jan 2026 → Jan 2028 expected biliary tract cancer Tongji Hospital Recruiting No outcome recorded
Phase 1/2 NCT07296341 Jan 2026 → Oct 2027 expected Shanghai Hengrui Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07229586 Dec 2025 → Dec 2027 expected neoplasm Shanghai Hengrui Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07073534 Jul 2025 → Dec 2027 expected Shanghai Hengrui Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07059221 Jul 2025 → Mar 2027 expected head and neck squamous cell carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06741020 Mar 2025 → Jun 2026 overdue hepatocellular carcinoma Zhejiang Cancer Hospital Recruiting No outcome recorded
Phase 1/2 NCT06597513 Dec 2024 → Dec 2025 overdue small cell lung carcinoma Zhou Chengzhi Not yet recruiting No outcome recorded
Phase 1/2 NCT06592287 Sep 2024 → Sep 2025 overdue gastric cancer Xianglin Yuan Not yet recruiting No outcome recorded
Phase 2174 trials
Phase 2 NCT07684040 Aug 2026 → Jul 2030 expected liver cancer Affiliated Hospital of Guangdong Medical University Not yet recruiting No outcome recorded
Phase 2 NCT07704645 Aug 2026 → Jun 2028 expected non-small cell lung carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07567326 Jul 2026 → Dec 2028 expected non-small cell lung carcinoma Peking University Cancer Hospital & Institute Not yet recruiting No outcome recorded
Phase 2 NCT07638436 Jun 2026 → Jan 2028 expected esophageal squamous cell carcinoma Sun Yat-sen University Recruiting No outcome recorded
Phase 2 NCT07584031 Jun 2026 → Dec 2027 expected esophageal squamous cell carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07624201 Jun 2026 → Jun 2028 expected urinary bladder carcinoma Harbin Medical University Not yet recruiting No outcome recorded
Phase 2 NCT07691593 Jun 2026 → Oct 2027 expected malignant pancreatic neoplasm Changhai Hospital Not yet recruiting No outcome recorded
Phase 2 NCT07687433 May 2026 → May 2028 expected rectal cancer Harbin Medical University Active not recruiting No outcome recorded
Phase 2 NCT07595770 May 2026 → Jan 2028 expected esophageal squamous cell carcinoma Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Recruiting No outcome recorded
Phase 2 NCT07452601 May 2026 → Feb 2027 expected esophageal squamous cell carcinoma Tang-Du Hospital Recruiting No outcome recorded
Show all 174 trials opens the full record — a long page
Phase 2/33 trials
Phase 2/3 NCT07454720 Mar 2026 → Nov 2032 expected Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 2/3 NCT06879145 Apr 2025 → Dec 2031 expected urinary bladder carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 2/3 NCT06335355 Mar 2024 → Oct 2028 expected non-small cell lung carcinoma Shanghai Shengdi Pharmaceutical Co., Ltd Not yet recruiting No outcome recorded
Phase 320 trials
Phase 3 NCT07691762 Jul 2026 → Apr 2031 expected hepatocellular carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT07679360 Jul 2026 → Dec 2030 expected triple-negative breast carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Not yet recruiting No outcome recorded
Phase 3 NCT07522151 May 2026 → Dec 2029 expected gastroesophageal cancer Shanghai Shengdi Pharmaceutical Co., Ltd Recruiting No outcome recorded
Phase 3 NCT07560358 May 2026 → Dec 2029 expected non-small cell lung carcinoma Cancer Institute and Hospital, Chinese Academy of Medical Sciences Not yet recruiting No outcome recorded
Phase 3 NCT07464327 Mar 2026 → Dec 2028 expected non-small cell lung carcinoma Hansoh BioMedical R&D Company Not yet recruiting No outcome recorded
Phase 3 NCT07393542 Feb 2026 → Sep 2027 expected urothelial carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT07229625 Jan 2026 → Dec 2029 expected biliary tract cancer Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT07238569 Dec 2025 → Dec 2029 expected nasopharyngeal carcinoma Sun Yat-sen University Not yet recruiting No outcome recorded
Phase 3 NCT07170995 Oct 2025 → Dec 2030 expected non-small cell lung carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 3 NCT07168200 Oct 2025 → Apr 2028 expected cervical cancer Shanghai Shengdi Pharmaceutical Co., Ltd Recruiting No outcome recorded
Phase 42 trials
Phase 4 NCT06417606 May 2024 → Apr 2025 intrahepatic cholangiocarcinoma Zhiyong Huang Unknown No outcome recorded
Phase 4 NCT06192186 Dec 2023 → Dec 2025 gastric adenocarcinoma Yang Jianjun, PhD Unknown No outcome recorded
Phase not applicable7 trials
NCT07388095 Feb 2026 → Feb 2027 expected esophageal squamous cell carcinoma Tianjin Medical University Cancer Institute and Hospital Not yet recruiting No outcome recorded
NCT06893887 May 2025 → Mar 2027 expected hepatocellular carcinoma Nanjing Tianyinshan Hospital Recruiting No outcome recorded
NCT06853678 Feb 2025 → Jul 2026 overdue small cell lung carcinoma Tianjin Medical University Cancer Institute and Hospital Recruiting No outcome recorded
NCT06480864 Aug 2024 → Aug 2025 overdue small cell lung carcinoma Yunpeng Liu Recruiting No outcome recorded
NCT06613113 Aug 2024 → Apr 2025 overdue colorectal cancer Ningbo Medical Center Lihuili Hospital Recruiting No outcome recorded
NCT06420908 May 2024 → May 2026 esophageal squamous cell carcinoma Hebei Medical University Fourth Hospital Withdrawn No outcome recorded
NCT05132790 Sep 2023 → Dec 2024 overdue breast cancer Shengjing Hospital Active not recruiting No outcome recorded
Also used as a comparator or background therapy in 35 trials
PhaseRegistry idDatesIndicationSponsorStatusOutcome
Phase 12 trials
Phase 1 NCT06350006 Background May 2024 → Dec 2027 expected Shanghai Hengrui Pharmaceutical Co., Ltd. Recruiting No outcome recorded
Phase 1 NCT05942378 Background Jul 2023 → Sep 2025 cancer Fudan University Unknown No outcome recorded
Phase 1/212 trials
Phase 1/2 NCT07239596 Background Jan 2026 → Dec 2030 expected renal cell carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT07105592 Background May 2025 → May 2027 expected head and neck squamous cell carcinoma Fudan University Recruiting No outcome recorded
Phase 1/2 NCT06840002 Background Mar 2025 → May 2026 overdue ovarian carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06703177 Background Feb 2025 → Jan 2026 overdue cancer Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 1/2 NCT06754930 Background Feb 2025 → Dec 2027 expected non-small cell lung carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 217 trials
Phase 2 NCT07682272 Background Jul 2026 → Jul 2027 expected hepatocellular carcinoma Suzhou Suncadia Biopharmaceuticals Co., Ltd. Not yet recruiting No outcome recorded
Phase 2 NCT07241767 Background Nov 2025 → Nov 2027 expected lung cancer Jiangsu HengRui Medicine Co., Ltd. Recruiting No outcome recorded
Phase 2 NCT07131514 Background Aug 2025 → Jun 2027 expected malignant pancreatic neoplasm Ruijin Hospital Recruiting No outcome recorded
Phase 2 NCT07137858 Comparator Aug 2025 → Jun 2027 expected oral cavity squamous cell carcinoma Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University Not yet recruiting No outcome recorded
Phase 2 NCT07071714 Background Jul 2025 → Oct 2031 expected colorectal cancer Suzhou Suncadia Biopharmaceuticals Co., Ltd. Recruiting No outcome recorded
Phase 2/31 trial
Phase 2/3 NCT06791460 Background Mar 2025 → Feb 2028 expected ovarian carcinoma Obstetrics & Gynecology Hospital of Fudan University Recruiting No outcome recorded
Phase 32 trials
Phase 3 NCT06675214 Background Jul 2024 → Jul 2027 expected nasopharyngeal carcinoma Sun Yat-sen University Recruiting No outcome recorded
Phase 3 NCT06092957 Background Oct 2023 → Oct 2029 expected nasopharyngeal carcinoma Sun Yat-sen University Recruiting No outcome recorded
Phase not applicable1 trial
NCT06702566 Background Jul 2024 → Jul 2026 overdue acute leukemia, cancer Tianjin Medical University Cancer Institute and Hospital Recruiting No outcome recorded

Evidence & citations 9 cited values

Every value below carries the sentence it was read from. 291 sources stand behind the page.

FieldValueCited text
Known as adebrelimab “This is a prospective, multicenter, randomized, uncontrolled Phase II study to assess the efficacy and safety of adebrelimab in combination with chemotherapy with or without...” NCT06775275
254

“Lenvatinib(oral,12mg once daily if body weight ≥60Kg; Body weight \< 60Kg, 8mg/ day); Adebrelimab(intravenous drip,1200mg once every 3 weeks); GEMOX(intravenous...” NCT06417606

“a) Camrelizumab 200mg, b) Toripalimab 240mg, or c) Adebrelimab 1200mg will be started on day 1 of induction chemotherapy and given every 3 weeks for up to 12 cycles, or until...” NCT06675214

“This prospective, single-arm, multicenter clinical study aims to preliminarily evaluate the efficacy and safety of Trastuzumab Rezetecan combined with Adebrelimab as...” NCT07624201

“Participants will receive the combination of Fruquintinib and Adebrelimab within 3 weeks after completion of high and low dose radiotherapy on metastases until disease...” NCT06613113

“Phase III Study of SHR-8068 Combined With Adebrelimab and Chemotherapy Versus Tislelizumab Combined With Chemotherapy in the Treatment of Locally Advanced or Metastatic...” NCT07170995

“TPF (Paclitaxel micelles or albumin-bound paclitaxel 100 mg/m2, cisplatin 30 mg/m2, fluorouracil 200 mg/m2 IV drip + 1000 mg/m2 pump for 44 hours, leucovorin/calcium 200 mg) +...” NCT07469241

Adebrelimab 1200 mg, repeated every 3 weeks, starting simultaneously with neoadjuvant chemotherapy and continuing for 1 year (including postoperative administration).” NCT06908668

“We aimed to assess the efficacy and safety of adebrelimab (SHR-1316), a novel anti-PD-L1 antibody, with standard chemotherapy as a first-line treatment for ES-SCLC.” PMID 35576956 May 2022

“After 4 cycles of concurrent chemoradiotherapy, the non-progressing subjects will continue to receive adebrelimab (1200 mg, IV, Q3W) maintenance therapy.” NCT07559786

“Immunotherapy consolidation began at the third cycle of chemotherapy: Adebrelimab 1200mg q3w to 2 year or disease progression” NCT06527898

“This study marks the first application of Adebrelimab in pediatric patients with Langerhans Cell Histiocytosis (LCH).” NCT06902792

“albumin-bound paclitaxel 260mg/m2, carboplatin AUC=5 and adebrelimab 1200mg were administered intravenously.” NCT07137858

“SHR-1316(Adebrelimab),20mg/kg,+Cisplatin 75mg/m2, d1+ etoposide 100mg/m2, d1,d2,d3, q3w, iv, 4 cycles.” NCT05496166

“Participants in the experimental arm will receive intravenous infusions of HS-20093 and adebrelimabNCT07464327

Adebrelimab is a recombinant humanized IgG4 monoclonal antibody with specificity for PD-L1.” NCT06455410

Adebrelimab Injection,intravenous infusion, Day 1, every 3 weeks for 2 cycles.” NCT07584031

“PD-L1 inhibitor includes durvalumab,Atezolizumab,Adebrelimab,Envafolimab.” NCT06702566

Adebrelimab was given intravenously, 600mg each time, once every 2 weeks” NCT04215003

“Radiotherapy followed by Adebrelimab+Bevacizumab+Cisplatin/Carboplatin” NCT07638852

“a) Camrelizumab 200mg, b) Toripalimab 240mg, or c) Adebrelimab 1200mg” NCT06092957

Adebrelimab (1200 mg) every three weeks intravenously” NCT06037655

Adebrelimab 1200mg day 1 q3w totally 4 to 6 cycles” NCT06479473

“Drug: Adebrelimab administered as an IV infusion” NCT05765032

“SHR-1316(Adebrelimab Injection)” NCT06237257

Adebrelimab, 1200mg,q3w,2 year” NCT06943235

adebrelimab: 1200 mg iv, q3w” NCT07560358

NCT06765616

NCT06480136

NCT07353684

NCT06385678

NCT06963502

NCT07691593

NCT06584227

NCT06385873

NCT07055841

NCT07284992

NCT06808971

NCT06375317

NCT07691762

NCT06592625

NCT06786312

NCT06277791

NCT06474468

NCT06703177

NCT06360042

NCT07266025

NCT06434103

NCT06531278

NCT07033143

NCT06433609

NCT07583550

NCT07615283

NCT06784206

NCT07131514

NCT06182800

NCT06839560

NCT06648525

NCT05932264

NCT06739928

NCT06913777

NCT07069270

NCT06280508

NCT07381543

NCT06672133

NCT06475209

NCT07357532

NCT07061210

NCT06247956

NCT06375642

NCT05353361

NCT06610734

NCT06840002

NCT06914050

NCT06741020

NCT06592287

NCT06282445

NCT06893887

NCT07670273

NCT07135544

NCT07704177

NCT06266832

NCT06389500

NCT07118527

NCT06737913

NCT07112833

NCT07007364

NCT07704645

NCT05975463

NCT06879145

NCT06452602

NCT07137039

NCT06916975

NCT07241793

NCT06692491

NCT05970666

NCT05924997

NCT06156267

NCT06506292

NCT06320301

NCT06254066

NCT06885814

NCT07522151

NCT07561775

NCT06464614

NCT06819319

NCT06475326

NCT07309185

NCT06869213

NCT07296341

NCT07317778

NCT07398560

NCT06192186

NCT06165900

NCT07031154

NCT06470672

NCT06446206

NCT07452601

NCT06261125

NCT06537505

NCT06470633

NCT07687433

NCT06350006

NCT06594874

NCT06485544

NCT07239596

NCT07543783

NCT06508229

NCT06853678

NCT06427239

NCT06236997

NCT06475417

NCT06349889

NCT06405061

NCT06208462

NCT06411457

NCT06547736

NCT06478264

NCT07668453

NCT05942378

NCT06618664

NCT04516681

NCT07110571

NCT07595172

NCT06776770

NCT06181032

NCT07684040

NCT06663059

NCT07595770

NCT06684158

NCT03736863

NCT07388095

NCT06234007

NCT07281209

NCT07063407

NCT06332170

NCT07554768

NCT06639347

NCT06439589

NCT07035392

NCT07569679

NCT07141264

NCT07059221

NCT05794477

NCT06424899

NCT07071714

NCT06735508

NCT06483282

NCT05753826

NCT06454448

NCT04770207

NCT07229625

NCT06178211

NCT06482788

NCT07229729

NCT06454578

NCT07567326

NCT06296563

NCT06332950

NCT06881017

NCT07638436

NCT07230301

NCT06773156

NCT06198465

NCT06685653

NCT07041437

NCT06298968

NCT06925516

NCT06177925

NCT06597513

NCT06299371

NCT06420908

NCT06199271

NCT06791460

NCT07682272

NCT06607276

NCT06771609

NCT06231017

NCT07457346

NCT06467617

NCT07200154

NCT06177522

NCT06092268

NCT05738317

NCT06614621

NCT06600841

NCT07105592

NCT06842472

NCT06229067

NCT06091124

NCT06510660

NCT06373133

NCT06146985

NCT06985602

NCT06482008

NCT06340230

NCT06562920

NCT06339619

NCT06339216

NCT06861894

NCT06418594

NCT07238569

NCT06335355

NCT05444088

NCT06766019

NCT07062328

NCT06500208

NCT06306560

NCT06251492

NCT06599216

NCT06149130

NCT07679360

NCT06417554

NCT07392541

NCT06513221

NCT06700421

NCT06225921

NCT06336707

NCT06149767

NCT06480864

NCT06599775

NCT07437898

NCT06749730

NCT06764368

NCT07393542

NCT06620848

NCT06512051

NCT06465563

NCT06699576

NCT06415669

NCT07192848

NCT05416775

NCT07073534

NCT07454720

NCT06844474

Known as ADE “intravenous infusion (IV) of Adebrelimab (ADE) (1200mg, IV, Q3W)” NCT06737913
Known as Adebrelimab Injection “-Generic Name: Adebrelimab Injection -Trade name: Ariel -English name: Adebrelimab Injection” NCT06902792
Known as Ariel “-Generic Name: Adebrelimab Injection -Trade name: Ariel -English name: Adebrelimab Injection” NCT06902792
Known as SHR-1316 “The therapeutic aim of Adebrelimab (SHR-1316) is to inhibit tumor growth by specifically blocking the binding of PD-1 to PD-L1 and terminating the immunosuppressive signals...” NCT06405061
45

“A Randomized, Double-blind, Multicenter Phase III Trial of Adebrelimab (SHR-1316) Plus S-1 and Oxaliplatin (SOX) Versus Placebo Plus S-1 and Oxaliplatin in the Perioperative...” NCT07522151

“The investigators will conduct a single-arm prospective study to evaluate the efficacy and safety of neoadjuvant therapy with adebrelimab (SHR-1316) and chemotherapy in...” NCT06178211

“Adebrelima(SHR-1316) is a recombinant humanized IgG4 antibody that binds efficiently and specifically to human and cynomolgus programmed cell death ligand 1 (PD-L1, CD274, or B7-H1)” NCT06375642

“Adebrelimab (SHR-1316) is a novel humanised IgG4 monoclonal antibody against PD-L1.” NCT07062328

“Adebrelimab (SHR-1316): injection, 600mg(12mL), intravenous infusion” NCT06439589

“adebrelimab (SHR-1316), a novel anti-PD-L1 antibody” PMID 35576956 May 2022

“Adebrelimab (SHR-1316) + Nab-paclitaxel + Cisplatin” NCT06869213

“Drug: SHR-1316 given intravenously (IV).” NCT04041011

SHR-1316(Adebrelimab Injection)” NCT06237257

NCT05198817

NCT05076682

NCT06474455

NCT04562337

NCT05082545

NCT05048134

NCT07028281

NCT05496166

NCT07466927

NCT05132790

NCT03133247

NCT06915142

NCT07241767

NCT07111832

NCT06754930

NCT05582499

NCT07009457

NCT03732508

NCT03995472

NCT07168200

NCT06778031

NCT04979390

NCT07268040

NCT07229586

NCT05205200

NCT05671822

NCT04316364

NCT04215471

NCT04647357

NCT03474289

NCT04400188

NCT04691063

NCT03711305

NCT06222879

NCT04303988

NCT05482568

Action Inhibit “Anti-PD-L1 antibody” NCT04647357
Modality Monoclonal antibody “SHR-1316 is a humanized IgG4 monoclonal antibodyNCT03133247
Route Intravenous “SHR-1316 administrated intravenously(IV)” NCT03474289
Target CD274 “binds efficiently and specifically to human and cynomolgus programmed cell death ligand 1 (PD-L1, CD274, or B7-H1)” NCT06375642