drugset / Trial / NCT07684040

A Study of Combination Therapy in Patients With Resectable Liver Cancer

NCT07684040

Phase 2 Not yet recruiting 68 enrolled Affiliated Hospital of Guangdong Medical University
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, single-arm clinical study designed to evaluate the efficacy and safety of an initial combination treatment strategy followed by surgery in patients with cancer. Eligible participants will receive combination therapy prior to surgical intervention. Patients who meet predefined surgical criteria will undergo hepatic resection. Following surgery, additional treatment may be administered according to the investigator's assessment. The primary objective is to evaluate time to treatment failure (TTF). Secondary objectives include evaluation of pathological response, resection outcomes, progression-related outcomes, survival outcomes, and safety.

Timeline

Start
2026-08-01
Primary completion
2030-07-01
Completion
2030-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Adebrelimab Monoclonal antibody
Subject Rivoceranib Small molecule

Indications