drugset / Trial / NCT06776770
A Phase Ib/II Study of Adebrelimab in Combination with Capecitabine and Oxaliplatin in Cancer
Phase 1/2
Recruiting
52 enrolled
Cancer Hospital Chinese Academy of Medical Science, Shenzhen Center
NaSingle-groupOpen-labelTreatment
Summary
In this study, the combination of Adebrelimab (PD-L1 monoclonal antibody) on the basis of standard treatment (two-drug chemotherapy regimen of fluorouracil and platinum drugs) may enhance the immune response in order to enhance the killing effect on tumor cells and bring survival benefits to patients with advanced or metastatic gastric cancer or gastroesophageal junction adenocarcinoma.
Timeline
- Start
- 2024-08-03
- Primary completion
- 2026-09-30
- Completion
- 2026-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Adebrelimab | Monoclonal antibody | 10 mg/kg | — |
| Subject | Adebrelimab | Monoclonal antibody | 20 mg/kg | — |
| Subject | Adebrelimab | Monoclonal antibody | 1200 mg | — |