drugset / Trial / NCT06222879

Study of HRS-8080 or SHR-A2009 Combined With Anti-tumor Therapy in Patients With Unresectable or Metastatic Breast Cancer

NCT06222879

Phase 1/2 Recruiting 350 enrolled Shandong Suncadia Medicine Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This study is designed to determine if treatments with the combination of HRS-8080 and SHR-A1811, the combination of HRS-8080 and SHR-A2009, the combination of SHR-A2009 and SHR-1316 are safe, tolerable, and has anti-cancer activity in patients with unresectable or metastatic breast cancer.

Timeline

Start
2024-02-20
Primary completion
2026-10-31
Completion
2026-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Adebrelimab Monoclonal antibody
Subject HRS-8080 Unknown
Subject SHR-A2009 Other / unclassified
Subject Trastuzumab Rezetecan Monoclonal antibody

Indications