drugset / Trial / NCT05943613

Efficacy of Intrathecal Clonidine Versus Neostigmine as Adjuvants to Bupivacaine on Postoperative Maternal and Fetal Outcomes After Elective Cesarean Section

NCT05943613

Phase 1 Unknown 111 enrolled Assiut University
RandomizedParallel-groupQuadruple-blindOther

Summary

The delivery of the infant into the arms of a conscious and pain free mother is one of the most exciting and rewarding moments in medicine. Neuraxial anesthesia is now the preferred technique for lower segment cesarean sections (LSCS). Although epidural, spinal, continuous spinal, and combined spinal-epidural techniques have all been advocated, most cesarean sections are performed under single-shot spinal anesthesia. Even when a long acting local anesthetic like bupivacaine is used, the duration of spinal anesthesia (SA) is short and higher doses of analgesics are required in the postoperative period. Therefore, achieving a subarachnoid block that provides high quality postoperative analgesia of consistently prolonged duration is an attractive goal.

Timeline

Start
2023-12-01
Primary completion
2025-09-30
Completion
2025-11-30

Drugs

EvaluationDrugModalityDoseRoute
Comparator Clonidine Other / unclassified 30 ug Intrathecal

Indications

No indication recorded.