drugset / Trial / NCT05960942
Application of Esketamine in Anesthesia of Autism Children
Completed
120 enrolled
The Second Hospital of Nanjing Medical University
Nanjing Medical University · collab
RandomizedParallel-groupQuadruple-blindOther
Summary
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. Autistic children appear with significant frequency for medical services, lots of which requiring procedural sedation or anaesthesia. Autistic children have often been described as difficult to sedate or anesthetize due to a variety of ASD symptoms. It is a challenging task to provide safe and effective sedation during the procedure of colonic TET for FMT in autism children. The investigators intend to explore an optimum anesthetic regimen for autism children undergoing endoscopic procedures.
Timeline
- Start
- 2023-08-01
- Primary completion
- 2023-10-30
- Completion
- 2023-10-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Esketamine | Other / unclassified | 0.3 mg/kg | — |
| Comparator | Sufentanil | Other / unclassified | 0.2 ug/kg | Intravenous |
| Comparator | Propofol | Small molecule | 2 mg/kg | Intravenous |