drugset / Trial / NCT05964647
Effect of Ketanserin, Olanzapine, and Lorazepam After LSD Administration on the Acute Response to LSD in Healthy Subjects
RandomizedCrossoverQuadruple-blindBasic science
Summary
The main objective of this study is to determine whether administration of ketanserin (40 mg), olanzapine (10 mg), and lorazepam (2 mg) after administration of LSD (150 µg) attenuates and shortens the subjective LSD response (any drug effect) compared to administration of LSD (150 µg) alone
Timeline
- Start
- 2024-02-01
- Primary completion
- 2025-06-30
- Completion
- 2025-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketanserin | Small molecule | 40 mg | Oral |
| Comparator | LSD | Unknown | 150 ug | Oral |
| Comparator | Lorazepam | Small molecule | 2 mg | Oral |
| Comparator | Olanzapine | Small molecule | 10 mg | Oral |
Indications
No indication recorded.