drugset / Trial / NCT05975580
Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery
Phase 4
Recruiting
120 enrolled
University of California, Irvine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
RandomizedSequentialQuadruple-blindTreatment
Summary
This is a randomized controlled trial employing a Sequential Multiple Assignment Randomized Trial (SMART) design to test whether pharmacotherapy, in conjunction with lifestyle counseling, can reverse weight regain after bariatric surgery.
Timeline
- Start
- 2023-08-29
- Primary completion
- 2027-07-31
- Completion
- 2028-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Phentermine | Small molecule | 15 mg | — |
| Subject | Phentermine | Small molecule | 30 mg | — |
| Subject | Topiramate | Small molecule | 50 mg | — |
| Subject | Topiramate | Small molecule | 100 mg | — |