drugset / Trial / NCT05975749

Adjuvant Serplulimab and Trastuzuma and Chemotherapy in Her-2+ Gastric Cancer

NCT05975749

Phase 2 Recruiting 114 enrolled Fudan University
RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to find out whether treatment with Serplulimab combined with Trastuzumab and Chemotherapy will improve the survival of gastric cancer patients with stage II-III after surgery.

Timeline

Start
2023-01-01
Primary completion
2026-01-01
Completion
2029-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Serplulimab Monoclonal antibody 4.5 mg/kg
Subject Trastuzuma Unknown 6 mg/kg
Background Capecitabine Small molecule 1000 mg/m2 Oral
Background Oxaliplatin Small molecule 130 mg/m2 Intravenous
Background S-1 Small molecule 40 mg/m2 Oral

Indications