drugset / Trial / NCT05993247
Efficacy of Probiotics for NSAID-induced Enteropathy in Arthritis Patients
RandomizedParallel-groupTriple-blindPrevention
Summary
This study aimed to investigate the efficacy of probiotics as a preventive agent for NSAID-induced enteropathy. Arthritis patients are randomly divided into probiotic and placebo groups, and the drug is administered for eight weeks. Before and after drug administration, the patient's symptoms/degree of small bowel injuries on capsule endoscopy/microbiome composition and diversity were investigated.
Timeline
- Start
- 2023-08-20
- Primary completion
- 2025-08-31
- Completion
- 2025-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bacillus subtilis | Vaccine | 150 mg | Oral |
| Subject | Clostridium Burtyricum Toa | Unknown | 150 mg | Oral |
| Subject | Saccharomyces boulardii | Other / unclassified | 113 mg | Oral |