drugset / Trial / NCT05994131
IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC
RandomizedParallel-groupOpen-labelTreatment
Summary
This is a multicenter, open-label, phase Ib/II clinical study to evaluate the safety, tolerability, pharmacokinetics and antitumor efficacy of IN10018 in combination with third-generation EGFR-TKI (Furmonertinib is the proposed) in previously-treated or naïve advanced EGFR-mutation positive NSCLC.
Timeline
- Start
- 2023-07-13
- Primary completion
- 2026-07-31
- Completion
- 2026-07-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Firmonertinib | Small molecule | — | Oral |
| Subject | Ifebemtinib | Small molecule | — | Oral |