drugset / Trial / NCT05994131

IN10018 Combination Therapy in Advanced EGFR Mutation-positive NSCLC

NCT05994131

Phase 1/2 Recruiting 110 enrolled InxMed (Shanghai) Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a multicenter, open-label, phase Ib/II clinical study to evaluate the safety, tolerability, pharmacokinetics and antitumor efficacy of IN10018 in combination with third-generation EGFR-TKI (Furmonertinib is the proposed) in previously-treated or naïve advanced EGFR-mutation positive NSCLC.

Timeline

Start
2023-07-13
Primary completion
2026-07-31
Completion
2026-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Firmonertinib Small molecule Oral
Subject Ifebemtinib Small molecule Oral