drugset / Trial / NCT06006273

A Phase Ib Trial of Eribulin in Combination With Irinotecan and Temozolamide in Children With Relapsed or Refractory Solid Tumors

NCT06006273

Phase 1 Recruiting 48 enrolled M.D. Anderson Cancer Center
RandomizedSingle-groupOpen-labelTreatment

Summary

To find the recommended dose of eribulin that can be given in combination with irinotecan and temozolomide to treat relapsed and/or refractory solid tumors.

Timeline

Start
2023-08-16
Primary completion
2026-12-31
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Eribulin Small molecule Intravenous
Background Irinotecan Small molecule Intravenous
Background Temozolomide Small molecule Oral