drugset / Trial / NCT06009055

Effects of Remimazolam and Propofol on Anesthesia Induction

NCT06009055

Unknown 80 enrolled Zheng Guo
RandomizedParallel-groupSingle-blindTreatment

Summary

The patients with diabetes who underwent laparoscopic cholecystectomy in the general surgery department of the Second Hospital of Shanxi Medical University were selected. The patients who were induced by remimazolam were included in the experimental group, and the patients who were induced by propofol were included in the control group. All the selected patients had no intimate relationship. The differences of blood pressure, heart rate and heart rate variability (HRV) between the experimental group and the control group were observed. According to the literature, it is speculated that the changes of blood pressure, heart rate and HRV indexes in the experimental group are smaller than those in the control group, and the difference is statistically significant.

Timeline

Start
2023-09-17
Primary completion
2024-11-30
Completion
2024-12-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Propofol Small molecule 2 mg/kg Other
Subject Remimazolam Small molecule 0.3 mg/kg Other