drugset / Trial / NCT06013241

A Study of the Efficacy and Safety of Brensocatib in Participants With Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP)

NCT06013241

Phase 2 Completed 288 enrolled Insmed Incorporated
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary purpose of the study is to evaluate the efficacy of brensocatib at 10 and 40 milligrams (mg) once daily (QD) compared with placebo in improving clinical symptoms of CRSsNP.

Timeline

Start
2023-10-30
Primary completion
2025-09-30
Completion
2025-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Brensocatib Small molecule 10 mg Oral
Subject Brensocatib Small molecule 40 mg Oral
Background Mometasone furoate Other / unclassified Intranasal