Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes

Summary

This study is conducted A- To investigate that PRF loaded with osteopromotive pharmacological drug can be a great aid in implant rehabilitation, and whether it could be a replacement for the other high price bone graft materials or not. This will be done through: 1. Measuring bone changes around the implant by cone beam 2. Measuring change in bone density around the implants B- Evaluate the effect of statins on osteoblasts activity and expression of various osteogenic products in vitro.

Timeline

Start

2021-01-05

Primary completion

2022-01-05

Completion

2023-02-05

Drugs

Indications