drugset / Trial / NCT06016530

Multi-level Molecular Profiling of Stress Exposure Under Standardized Food Intake: A Clinical Study

NCT06016530 ↗

Unknown 30 enrolled Dr. Nils Gassen
NaSingle-groupOpen-labelBasic science

Summary

Nutrition plays a crucial role in preventing various diseases, including cardiovascular and metabolic conditions. Moreover, it is gaining increasing attention in the context of preventing and treating psychiatric disorders. However, limited knowledge exists concerning the effects of food intake and stress on metabolism over time. To enhance the understanding of this subject, blood components in healthy volunteers will be examined during a standardized diet, focusing on the interaction between nutrition and stress. Physiological stress will be induced by subjecting participants to sleep deprivation for over 36 hours. Hormonal influences related to the female menstrual cycle are particularly taken into account in female participants. In conclusion, comprehending these processes can improve the understanding of nutritional physiology and contribute to advancements in clinical practice.

Timeline

Start
2023-03-21
Primary completion
2024-12-31
Completion
2025-03-01

Publications

Drugs

EvaluationDrugModalityDoseRoute
Subject Dexamethasone Small molecule 1 mg —

Indications