drugset / Trial / NCT06020898
Sodium Valproate in Patients With Acute Ischemic Stroke
RandomizedParallel-groupSingle-blindTreatment
Summary
The purpose of this pilot trial is to investigate the feasibility, safety, and efficacy of sodium valproate in patients with acute ischemic stroke, and also explore the mechanism: whether valproate increases peripheral anti-inflammatory CD177+ neutrophil levels.
Timeline
- Start
- 2023-09-01
- Primary completion
- 2024-04-30
- Completion
- 2024-04-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Valproic Acid | Small molecule | 10 mg/kg | Intravenous |
| Subject | Valproic Acid | Small molecule | 20 mg/kg | Intravenous |