drugset / Trial / NCT06025630
Targeting Endoplasmic Reticulum Stress in Human Hypertension
RandomizedParallel-groupSingle-blindBasic science
Summary
There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill this gap by performing a single-blind, placebo-controlled trial in humans with hypertension.
Timeline
- Start
- 2023-08-15
- Primary completion
- 2028-12-31
- Completion
- 2028-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Taurursodiol | Small molecule | 1750 mg | Oral |