drugset / Trial / NCT06025630

Targeting Endoplasmic Reticulum Stress in Human Hypertension

NCT06025630

Phase 1/2 Recruiting 70 enrolled University of North Texas Health Science Center
RandomizedParallel-groupSingle-blindBasic science

Summary

There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill this gap by performing a single-blind, placebo-controlled trial in humans with hypertension.

Timeline

Start
2023-08-15
Primary completion
2028-12-31
Completion
2028-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Taurursodiol Small molecule 1750 mg Oral

Indications