drugset / Trial / NCT06026319

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

NCT06026319 ↗

Phase 1 Recruiting 24 enrolled Massachusetts General Hospital
NaSingle-groupOpen-labelTreatment

Summary

This research study involves the study of CD79b-19 CAR T cells for treating people with relapsed/refractory Non-Hodgkin Lymphoma and to understand the side effects when treated with CD79b-19 CAR T cells. This research study involves the study drugs: * CD79b-19 CAR T cells * Fludarabine and Cyclophosphamide: Standardly used chemotherapy drugs as part of lymphodepleting process

Timeline

Start
2023-10-26
Primary completion
2027-01-01
Completion
2028-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CD79b-19 CAR T cells Cell therapy — Intravenous
Background Cyclophosphamide Other / unclassified — Intravenous
Background Fludarabine Small molecule — Intravenous