drugset / Trial / NCT06030713

Timing of Maternal Antibiotic Prophylaxis During a Cesarean Section and the Early Infant Gut Microbiome

NCT06030713

Completed 33 enrolled University Medical Center Groningen
RandomizedParallel-groupSingle-blindPrevention

Summary

In this study, investigators seek to determine whether the timing of antibiotics given to mothers during an elective C-section affects the composition of their infant's gut microbiome. To do this, a randomized controlled trial (RCT) was carried out with women undergoing elective C-sections. These women were either given antibiotics before the skin incision (AB+) or after the umbilical cord was clamped (AB-).

Timeline

Start
2019-03-01
Primary completion
2022-10-01
Completion
2023-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Cefazolin Small molecule 1 g Intravenous

Indications