NAC vs Placebo on Opioid Use for Hysterectomy

Phase 3 Recruiting 240 enrolled Medical University of South Carolina

RandomizedParallel-groupTriple-blindTreatment

Summary

This study will enroll females who are ages 18 and older undergoing a laparoscopic or robotic, partial or full hysterectomy. Participants will be randomized to receive IV n-acetylcysteine or placebo during the first 60 minutes of their procedure. At various time points after the procedure patients will be asked to report their pain scores, and any pain medication taken.

Timeline

Start: 2023-11-30
Primary completion: 2026-11-25
Completion: 2026-12-09

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	N-acetylcysteine	Small molecule	150 mg/kg	Intravenous

Indications

No indication recorded.