drugset / Trial / NCT06041776

Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations

NCT06041776

Phase 3 Recruiting 570 enrolled Betta Pharmaceuticals Co., Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This multicenter, randomized, controlled, double-blind, double-simulated, Phase III study is designed to evaluate the efficacy and safety of Befotertinib compared with Icotinib as adjuvant treatment in EGFR-sensitive mutation-positive stage IB-IIIB (T3N2M0) non-small cell lung cancer after surgical resection.

Timeline

Start
2023-03-28
Primary completion
2028-04-30
Completion
2029-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Befotertinib Small molecule 100 mg Oral
Comparator Icotinib Small molecule 125 mg Oral