drugset / Trial / NCT06041776
Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This multicenter, randomized, controlled, double-blind, double-simulated, Phase III study is designed to evaluate the efficacy and safety of Befotertinib compared with Icotinib as adjuvant treatment in EGFR-sensitive mutation-positive stage IB-IIIB (T3N2M0) non-small cell lung cancer after surgical resection.
Timeline
- Start
- 2023-03-28
- Primary completion
- 2028-04-30
- Completion
- 2029-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Befotertinib | Small molecule | 100 mg | Oral |
| Comparator | Icotinib | Small molecule | 125 mg | Oral |